Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6FHT
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| Drug Name |
(S)-1-{(S)-2-[((2S,3S)-3-Isobutylcarbamoyl-oxiranecarbonyl)-amino]-3-methyl-pentanoyl}-pyrrolidine-2-carboxylic acid
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| Synonyms |
CHEMBL1790799
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C19H31N3O6
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| Canonical SMILES |
CC[C@@H](C)[C@H](NC(=O)[C@H]1O[C@@H]1C(=O)NCC(C)C)C(=O)N2CCC[C@H]2C(=O)O
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| InChI |
InChI=1S/C19H31N3O6/c1-5-11(4)13(18(25)22-8-6-7-12(22)19(26)27)21-17(24)15-14(28-15)16(23)20-9-10(2)3/h10-15H,5-9H2,1-4H3,(H,20,23)(H,21,24)(H,26,27)/t11-,12+,13+,14+,15+/m1/s1
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| InChIKey |
HXRQFZARHUWLAH-QTVXIADOSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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