Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6N4H
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| Drug Name |
9-(3-hydroxypropyl)-6-(3-(thiophen-2-yl)benzylamino)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL525165
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H18N6OS
|
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| Canonical SMILES |
OCCCn1cnc2c(NCc3cccc(c3)c4cccs4)nc(nc12)C#N
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| InChI |
InChI=1S/C20H18N6OS/c21-11-17-24-19(18-20(25-17)26(13-23-18)7-3-8-27)22-12-14-4-1-5-15(10-14)16-6-2-9-28-16/h1-2,4-6,9-10,13,27H,3,7-8,12H2,(H,22,24,25)
|
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| InChIKey |
NHSUTAMAYPVEKR-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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