Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8JQP
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| Drug Name |
(R)-2-((S)-1-(4-bromophenyl)-2,2,2-trifluoroethylamino)-N-(1-cyanocyclopropyl)-3-(methylsulfinyl)propanamide
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| Synonyms |
CHEMBL436636
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C16H17BrF3N3O2S
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| Canonical SMILES |
C[S+]([O-])C[C@H](N[C@@H](c1ccc(Br)cc1)C(F)(F)F)C(=O)NC2(CC2)C#N
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| InChI |
InChI=1S/C16H17BrF3N3O2S/c1-26(25)8-12(14(24)23-15(9-21)6-7-15)22-13(16(18,19)20)10-2-4-11(17)5-3-10/h2-5,12-13,22H,6-8H2,1H3,(H,23,24)/t12-,13-,26?/m0/s1
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| InChIKey |
WKOXXQWORKCMDZ-GXXHEZNASA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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