Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXEG9F
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| Drug Name |
1-(1-(3,5-bis(trifluoromethyl)phenyl)-3-phenylpropylidene)thiosemicarbazide
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| Synonyms |
CHEMBL410086
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C18H15F6N3S
|
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| Canonical SMILES |
NC(=S)N\\N=C(/CCc1ccccc1)\\c2cc(cc(c2)C(F)(F)F)C(F)(F)F
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| InChI |
InChI=1S/C18H15F6N3S/c19-17(20,21)13-8-12(9-14(10-13)18(22,23)24)15(26-27-16(25)28)7-6-11-4-2-1-3-5-11/h1-5,8-10H,6-7H2,(H3,25,27,28)/b26-15+
|
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| InChIKey |
JFGRHCAKWZRTBW-CVKSISIWSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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