Drug Information
Drug General Information | |||||
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Drug ID |
DXH3IM
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Drug Name |
7-(3-(3,3-difluoroazetidin-1-yl)propoxy)-4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
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Synonyms |
CHEMBL396703
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Indication | Discovery agent | Investigative | [1] | ||
Formula |
C23H28F2N2O2
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Canonical SMILES |
COc1ccc(cc1)C2CN(C)Cc3cc(OCCCN4CC(F)(F)C4)ccc23
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InChI |
InChI=1S/C23H28F2N2O2/c1-26-13-18-12-20(29-11-3-10-27-15-23(24,25)16-27)8-9-21(18)22(14-26)17-4-6-19(28-2)7-5-17/h4-9,12,22H,3,10-11,13-16H2,1-2H3
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InChIKey |
AUMQJULFKZREJZ-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Histamine H3 receptor | Target Info | [1] | ||
Sodium-dependent serotonin transporter | Target Info | [1] | |||
KEGG Pathway | Neuroactive ligand-receptor interactionhsa04726:Serotonergic synapse | ||||
NetPath Pathway | TCR Signaling Pathway | ||||
PANTHER Pathway | 5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | |||||
5HT3 type receptor mediated signaling pathway | |||||
5HT4 type receptor mediated signaling pathway | |||||
Reactome | Histamine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Monoamine Transport | ||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP727:Monoamine Transport | |||||
SIDS Susceptibility Pathways | |||||
NRF2 pathway | |||||
Synaptic Vesicle Pathway | |||||
Serotonin Transporter Activity | |||||
References | |||||
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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