Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXPI5U
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| Drug Name |
[(S)-2-Naphthalen-2-yl-1-((5S,6R)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL323638
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H25N3O6S
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| Canonical SMILES |
O=C(N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H]3[C@H]4N(CCS4(=O)=O)C3=O)OCc5ccccc5
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| InChI |
InChI=1S/C26H25N3O6S/c30-23(28-22-24(31)29-12-13-36(33,34)25(22)29)21(27-26(32)35-16-17-6-2-1-3-7-17)15-18-10-11-19-8-4-5-9-20(19)14-18/h1-11,14,21-22,25H,12-13,15-16H2,(H,27,32)(H,28,30)/t21-,22+,25-/m0/s1
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| InChIKey |
XJEBMYGPXQJVFF-FBLLAGFSSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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