Drug General Information
Drug ID
DXV5U3
Drug Name
(+/-)-(2-(1-(3,4-dichlorophenyl)ethyl)phenyl)-N,N-dimethylmethanamine
Synonyms
CHEMBL493667
Indication Discovery agent Investigative [1587926]
Formula
C17H19Cl2N
Canonical SMILES
CC(c1ccc(Cl)c(Cl)c1)c2ccccc2CN(C)C
InChI
InChI=1S/C17H19Cl2N/c1-12(13-8-9-16(18)17(19)10-13)15-7-5-4-6-14(15)11-20(2)3/h4-10,12H,11H2,1-3H3
InChIKey
LLTVABOFFOVVKQ-UHFFFAOYSA-N
Target and Pathway
Target(s) 5-hydroxytryptamine 1B receptor Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP727:Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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