Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXW9S4
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| Drug Name |
9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamino)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL497237
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H18N6OS
|
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| Canonical SMILES |
OCCCn1cnc2c(NCc3cccc(c3)c4ccsc4)nc(nc12)C#N
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| InChI |
InChI=1S/C20H18N6OS/c21-10-17-24-19(18-20(25-17)26(13-23-18)6-2-7-27)22-11-14-3-1-4-15(9-14)16-5-8-28-12-16/h1,3-5,8-9,12-13,27H,2,6-7,11H2,(H,22,24,25)
|
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| InChIKey |
ROQSYDCGYWIBSQ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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