Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXX3J7
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| Drug Name |
2-tert-Butyloxycarbonylamino-6,7-methylenedioxy-1-(4-methoxyphenyl)-2H-isoquinolin-3-one
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| Synonyms |
CHEMBL594179
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H22N2O6
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| Canonical SMILES |
COc1ccc(cc1)C2=C3C=C4OCOC4=CC3=CC(=O)N2NC(=O)OC(C)(C)C
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| InChI |
InChI=1S/C22H22N2O6/c1-22(2,3)30-21(26)23-24-19(25)10-14-9-17-18(29-12-28-17)11-16(14)20(24)13-5-7-15(27-4)8-6-13/h5-11H,12H2,1-4H3,(H,23,26)
|
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| InChIKey |
GLQYBHSWTNIFJZ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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