Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXY13O
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| Drug Name |
(S)-N-(1-(cyanomethylamino)-1-oxo-3-(3-(pyridazin-3-yl)phenyl)propan-2-yl)benzamide
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| Synonyms |
CHEMBL556436
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H19N5O2
|
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| Canonical SMILES |
O=C(NCC#N)[C@H](Cc1cccc(c1)c2cccnn2)NC(=O)c3ccccc3
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| InChI |
InChI=1S/C22H19N5O2/c23-11-13-24-22(29)20(26-21(28)17-7-2-1-3-8-17)15-16-6-4-9-18(14-16)19-10-5-12-25-27-19/h1-10,12,14,20H,13,15H2,(H,24,29)(H,26,28)/t20-/m0/s1
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| InChIKey |
BKBPVMYBRCWYHF-FQEVSTJZSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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