Drug Information

Drug General Information
Drug ID
D02KIE
Former ID
DNAP001548
Drug Name
Cimetropium bromide
Synonyms
Alginor (TN)
Drug Type
Small molecular drug
Indication Gastric motility disorder; Spasm [ICD9: 728.85; ICD10:K22.4, R25.2] Approved [551871]
Company
DeAngelini
Structure
Download
2D MOL

3D MOL
Formula
C21H28BrNO4
Canonical SMILES
C[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)CC5CC5.[Br<br />-]
InChI
1S/C21H28NO4.BrH/c1-22(11-13-7-8-13)17-9-15(10-18(22)20-19(17)26-20)25-21(24)16(12-23)14-5-3-2-4-6-14;/h2-6,13,15-20,23H,7-12H2,1H3;1H/q+1;/p-1/t15?,16-,17-,18+,19-,20+,22?;/m0./s1
InChIKey
WDURTRGFUGAJHA-MMQBYREUSA-M
CAS Number
CAS 51598-60-8
PubChem Compound ID
6917944
PubChem Substance ID
12013732, 52302741, 57371742, 92720221, 126620166, 223672104
SuperDrug ATC ID
A03BB05
Target and Pathway
Target(s) Muscarinic acetylcholine receptor M5 Target Info Modulator [528603], [536361]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Regulation of actin cytoskeleton
PANTHER Pathway Alzheimer disease-amyloid secretase pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Muscarinic acetylcholine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
Regulation of Actin Cytoskeleton
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 528603Scopolamine in Brugmansia suaveolens (Solanaceae): defense, allocation, costs, and induced response. J Chem Ecol. 2007 Feb;33(2):297-309.
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.