Drug General Information
Drug ID	D03PRV
Former ID	DIB015612
Drug Name	BGC-20-1259
Synonyms	RS-1259
Drug Type	Small molecular drug
Indication	Parkinson's disease [ICD9: 332; ICD10:G20]		Phase 1	[526830]
Company	Sankyo Co Ltd
Structure		Download 2D MOL 3D MOL
Formula	C42H50N6O14
Canonical SMILES	[N+](=O)(c1ccc(cc1)OCC[C@@H](c1ccc(OC(=O)N(C)C)cc1)NC)[<br />O-].C(=O)(/C=C/C(=O)O)O
PubChem Compound ID	6918634
Target and Pathway
Target(s)	Sodium-dependent serotonin transporter	Target Info	Modulator
KEGG Pathway	Serotonergic synapse
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathway
WikiPathways	Monoamine Transport
	SIDS Susceptibility Pathways
	NRF2 pathway
	Synaptic Vesicle Pathway
	Serotonin Transporter Activity
References
Ref 526830	Pharmacological characterization of RS-1259, an orally active dual inhibitor of acetylcholinesterase and serotonin transporter, in rodents: possible treatment of Alzheimer's disease. J Pharmacol Sci.2003 Sep;93(1):95-105.

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