TTD | Drug: D03WBX

Drug General Information
Drug ID	D03WBX
Former ID	DIB020439
Drug Name	MRS2782
Synonyms	Uridine-5'-alpha,beta-methylene-diphosphate triethylammonium salt
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539099]
Structure		Download 2D MOL
Formula	C10H16N2O11P2
InChI	InChI=1S/C10H16N2O11P2/c13-6-1-2-12(10(16)11-6)9-8(15)7(14)5(23-9)3-22-25(20,21)4-24(17,18)19/h1-2,5,7-9,14-15H,3-4H2,(H,20,21)(H,11,13,16)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1
InChIKey	PDEGDTTUBZXACY-ZOQUXTDFSA-N
PubChem Compound ID	44585949
PubChem Substance ID	99239585, 103641033, 104116082, 135650665, 164164959
Target and Pathway
Target(s)	P2Y purinoceptor 6	Target Info	Agonist	[529505]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
Reactome	P2Y receptors
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539099	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1748).
Ref 529505	Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg Med Chem. 2008 Jun 15;16(12):6319-32.

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Drug Information