Drug Information

Drug General Information
Drug ID
D04ANO
Former ID
DIB018987
Drug Name
BMS compound 87b
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540431]
Formula
C27H37N3O3
InChI
InChI=1S/C27H37N3O3/c1-3-26(32)25-18-22(17-21-9-5-4-6-10-21)13-16-30(25)15-8-14-28-27(33)29-24-12-7-11-23(19-24)20(2)31/h4-7,9-12,19,22,25-26,32H,3,8,13-18H2,1-2H3,(H2,28,29,33)/t22-,25-,26+/m1/s1
InChIKey
UEKNCACYTQCRSI-RCXJIHSJSA-N
PubChem Compound ID
9868459
PubChem Substance ID
14983821, 45290723, 77778365, 103234637, 104009000, 104009022, 142548039, 178100481, 248765219
Target and Pathway
Target(s) mRNA of CCR3 chemokine Target Info Antagonist [526362]
NetPath Pathway IL3 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
References
Ref 540431(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3492).
Ref 526362CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1785-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.