Drug Information

Drug General Information
Drug ID
D05QAD
Former ID
DIB020832
Drug Name
RO320-2947/001
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542832]
Structure
Download
2D MOL
Formula
C26H36ClN3O5
InChI
InChI=1S/C26H36ClN3O5/c1-17(31)22(16-30-11-9-19(10-12-30)13-18-5-7-20(27)8-6-18)29-26(32)28-21-14-23(33-2)25(35-4)24(15-21)34-3/h5-8,14-15,17,19,22,31H,9-13,16H2,1-4H3,(H2,28,29,32)/t17?,22-/m0/s1
InChIKey
JYDVJNOBDUOZJC-UGNFMNBCSA-N
PubChem Compound ID
10255622
PubChem Substance ID
15259001, 22637710, 41240874, 77471381, 135650915, 227455938
Target and Pathway
Target(s) mRNA of CCR3 chemokine Target Info Antagonist [526363]
NetPath Pathway IL3 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
References
Ref 542832(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 791).
Ref 526363Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med. 2002 Jun 15;165(12):1602-9.

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