Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06OMW
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| Former ID |
DAP001107
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| Drug Name |
Rasagiline
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| Synonyms |
RAS; Rasagiline [INN]; Azilect (TN); Rasagiline (INN); (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine; (1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine; (R)-N-2-Propynyl-1-indanamine; 1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-, (1R)
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antiparkinson Agents
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| Company |
Teva Pharmaceutical Industries Ltd
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| Structure |
|
Download2D MOL |
|||
| Formula |
C12H13N
|
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| InChI |
InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1
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| InChIKey |
RUOKEQAAGRXIBM-GFCCVEGCSA-N
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| CAS Number |
CAS 136236-51-6
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7890222, 7980093, 10056118, 15120458, 15219503, 36118694, 46506045, 46511554, 50070333, 50071312, 56313239, 61269083, 80749168, 92713124, 96025155, 103233337, 111619048, 121277906, 121362276, 126573831, 126625000, 126656198, 126667056, 126732599, 129184029, 132554079, 134338352, 134358863, 135228398, 135611108, 135683150, 136340364, 136373590, 137001346, 142523977, 143493292, 144076117, 151977094, 152165036, 152234171, 160816897, 160964654, 162011569, 162204826, 163090554, 164848146, 172090451, 172859758, 174479357, 175267772
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| SuperDrug ATC ID |
N04BD02
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| SuperDrug CAS ID |
cas=136236516
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| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] B | Target Info | Inhibitor | [537470] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| Pathway Interaction Database | Alpha-synuclein signaling | ||||
| References | |||||
| Ref 536285 | Novel pharmacological targets for the treatment of Parkinson's disease. Nat Rev Drug Discov. 2006 Oct;5(10):845-54. | ||||
| Ref 541751 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6641). | ||||
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