Target Information

Target General Infomation
Target ID
T83011
Former ID
TTDS00341
Target Name
Amine oxidase [flavin-containing] B
Gene Name
MAOB
Synonyms
MAO-B; Monoamine oxidase; Monoamine oxidase B; MAOB
Target Type
Successful
Disease Alzheimer disease [ICD9: 331; ICD10: G30]
Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10: A00-B99]
Central nervous system disease [ICD10: G00-G99]
Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10: F01-F07, F04, F05, R41.3]
Depression; Anxiety disorder [ICD9:311, 300; ICD10: F30-F39, F32, F40-F42]
Dementia [ICD9: 290-294; ICD10: F01-F07]
Idiopathic parkinson's disease [ICD9: 332; ICD10: F02.3, G20]
Major depressive episode without melancholia [ICD10: F30-F39]
Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10: F32, F33, M32]
Moderate to severe hypertension [ICD10: I10-I16]
Motor symptoms; Parkinson's disease [ICD9: 332, 335.2; ICD10: F02.3, G12.2, G20]
Neurodegenerative disease [ICD9: 330-337; ICD10: G30-G32]
Neuropathic pain [ICD9: 356.0, 356.8; ICD10: G64, G90.0]
Obesity [ICD9: 278; ICD10: E66]
Parkinson's disease [ICD9: 332; ICD10: G20]
Vitiligo [ICD9: 709.01; ICD10: L80]
Unspecified [ICD code not available]
Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
BioChemical Class
Oxidoreductases acting on CH-NH2 group of donors
Target Validation
T83011
UniProt ID
P27338
EC Number
EC 1.4.3.4
Sequence
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
Drugs and Mode of Action
Drug(s) Indeloxazine Drug Info Approved Dementia [551871]
Pargyline Drug Info Approved Moderate to severe hypertension [551871]
Phenelzine Drug Info Approved Depression; Anxiety disorder [538452], [542285], [551871]
Rasagiline Drug Info Approved Parkinson's disease [536285], [541751]
Safinamide Drug Info Approved Parkinson's disease [889446]
Selegiline Drug Info Approved Major depressive disorder [522265], [541748]
Selegiline Hydrochloride Drug Info Approved Parkinson's disease [551871]
Tranylcypromine Drug Info Approved Major depressive episode without melancholia [551871]
Psoralen Drug Info Phase 3 Discovery agent [524054]
Safinamide Drug Info Phase 3 Idiopathic parkinson's disease [536923], [543044]
TRYPTAMINE Drug Info Phase 3 Discovery agent [521730], [538764]
P2B-001 Drug Info Phase 2/3 Parkinson's disease [524487]
CHF-3381 Drug Info Phase 2 Neuropathic pain [529017], [536374]
Ladostigil Drug Info Phase 2 Alzheimer disease [531772]
RG1577 Drug Info Phase 2 Alzheimer disease [548499]
Neu-120 Drug Info Phase 1/2 Parkinson's disease [522217]
PIPERINE Drug Info Phase 1/2 Vitiligo [523529], [539613]
PF9601N Drug Info Phase 1 Parkinson's disease [529304]
RWJ-416457 Drug Info Preclinical Bacterial infections [547487]
Lazabemide Drug Info Discontinued in Phase 3 Cognitive disorders [541750], [545650]
MOFEGILINE Drug Info Discontinued in Phase 3 Cognitive disorders [545271]
EVT-301 Drug Info Discontinued in Phase 1 Alzheimer disease [548293]
HT-1067 Drug Info Discontinued in Phase 1 Parkinson's disease [549231]
SL-25.1188 Drug Info Discontinued in Phase 1 Alzheimer disease [547083]
Milacemide Drug Info Terminated Alzheimer disease [530942]
Inhibitor (+/-)-2-(4'-Benzyloxyphenyl)thiomorpholin-5-one Drug Info [530683]
(+/-)-2-(4'-Benzyloxyphenyl)thiomorpholine Drug Info [530683]
(+/-)-2-(4'-Butoxyphenyl)thiomorpholin-5-one Drug Info [530683]
(+/-)-2-(4'-Butoxyphenyl)thiomorpholine Drug Info [530683]
(+/-)-2-(4'-Ethoxyphenyl)thiomorpholin-5-one Drug Info [530683]
(+/-)-2-(4'-Ethoxyphenyl)thiomorpholine Drug Info [530683]
(+/-)-2-(4'-Methoxyphenyl)thiomorpholin-5-one Drug Info [530683]
(+/-)-2-(4'-Methoxyphenyl)thiomorpholine Drug Info [530683]
(+/-)-2-(4'-Propoxyphenyl)thiomorpholin-5-one Drug Info [530683]
(+/-)-2-(4'-Propoxyphenyl)thiomorpholine Drug Info [530683]
(+/-)-2-(4-fluorophenyl)-7-methoxychroman-4-one Drug Info [530614]
(+/-)-2-(4-fluorophenyl)-7-methylchroman-4-one Drug Info [530614]
(+/-)-2-(4-fluorophenyl)chroman-4-one Drug Info [530614]
(+/-)-2-(4-methoxyphenyl)-7-methylchroman-4-one Drug Info [530614]
(+/-)-2-p-tolylchroman-4-one Drug Info [530614]
(+/-)-2-Phenylthiomorpholin-5-one Drug Info [530683]
(+/-)-2-Phenylthiomorpholine Drug Info [530683]
(+/-)-7-fluoro-2-(4-fluorophenyl)chroman-4-one Drug Info [530614]
(+/-)-7-fluoro-2-(4-methoxyphenyl)chroman-4-one Drug Info [530614]
(+/-)-7-fluoro-2-p-tolylchroman-4-one Drug Info [530614]
(+/-)-7-fluoro-2-phenylchroman-4-one Drug Info [530614]
(+/-)-7-methoxy-2-(4-methoxyphenyl)chroman-4-one Drug Info [530614]
(+/-)-7-methoxy-2-p-tolylchroman-4-one Drug Info [530614]
(+/-)-7-methoxy-2-phenylchroman-4-one Drug Info [530614]
(+/-)-7-methyl-2-p-tolylchroman-4-one Drug Info [530614]
(+/-)-7-methyl-2-phenylchroman-4-one Drug Info [530614]
(6-Benzyloxy-2-naphthyl)-2-aminopropane Drug Info [529986]
(6-Ethoxy-2-naphthyl)-2-aminopropane Drug Info [529986]
(6-Methoxy-2-naphthyl)-2-aminopropane Drug Info [529986]
(6-Propoxy-2-naphthyl)-2-aminopropane Drug Info [529986]
(7-Benzyloxy-2-oxo-2H-chromen-4-yl)acetonitrile Drug Info [530434]
(E)-5-(3-Chlorostyryl)isatin Drug Info [530056]
(E)-5-(3-Fluorostyryl)isatin Drug Info [530056]
(E)-5-Styrylisatin Drug Info [530056]
(E)-6-Styrylisatin Drug Info [530056]
(E)-8-(3-chlorostyryl)-caffeine Drug Info [530425]
(R)(+)-2-(4-fluorophenyl)-7-methoxychroman-4-one Drug Info [530614]
(R)(+)-7-fluoro-2-(4-fluorophenyl)chroman-4-one Drug Info [530614]
(R)(+)-7-fluoro-2-p-tolylchroman-4-one Drug Info [530614]
(R)(+)-7-fluoro-2-phenylchroman-4-one Drug Info [530614]
(R)(+)-7-methyl-2-p-tolylchroman-4-one Drug Info [530614]
(R)(+)-7-methyl-2-phenylchroman-4-one Drug Info [530614]
(R)-3-Prop-2-ynylamino-indan-5-ol Drug Info [527719]
(R)-Indan-1-yl-methyl-prop-2-ynyl-amine Drug Info [527719]
(R)-N2-{4-[(3-chlorobenzyl)oxy]benzyl}alaninamide Drug Info [529025]
(R)-N2-{4-[(3-chlorobenzyl)oxy]benzyl}serinamide Drug Info [529025]
(R)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}alaninamide Drug Info [529025]
(R/R)BEFLOXATONE Drug Info [526287]
(S)(+)-2-(4-fluorophenyl)-7-methoxychroman-4-one Drug Info [530614]
(S)(+)-7-fluoro-2-(4-fluorophenyl)chroman-4-one Drug Info [530614]
(S)(+)-7-fluoro-2-p-tolylchroman-4-one Drug Info [530614]
(S)(+)-7-fluoro-2-phenylchroman-4-one Drug Info [530614]
(S)(+)-7-methyl-2-p-tolylchroman-4-one Drug Info [530614]
(S)(+)-7-methyl-2-phenylchroman-4-one Drug Info [530614]
(S)-2-amino-1-(4-butylthiophenyl)-propane Drug Info [528855]
(S)-2-amino-1-(4-propylthiophenyl)-propane Drug Info [528855]
(S)-N2-[4-(benzyloxy)benzyl]alaninamide Drug Info [529025]
(S)-N2-[4-(benzyloxy)benzyl]serinamide Drug Info [529025]
(S)-N2-{4-[(3-chlorobenzyl)oxy]benzyl}alaninamide Drug Info [529025]
(S)-N2-{4-[(3-chlorobenzyl)oxy]benzyl}serinamide Drug Info [529025]
(S)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}serinamide Drug Info [529025]
(S)-N2-{4-[(4-chlorobenzyl)oxy]benzyl}alaninamide Drug Info [529025]
(S)-N2-{4-[(4-chlorobenzyl)oxy]benzyl}serinamide Drug Info [529025]
(S)-N2-{4-[(4-nitrobenzyl)oxy]benzyl}serinamide Drug Info [529025]
1,2,3,4-Tetrahydro-naphthalen-1-ylamine Drug Info [533451]
1,2,3,4-Tetrahydro-pyrazino[1,2-a]indole Drug Info [526994]
1,4-diphenyl-(1E,3E)-1,3-butadiene Drug Info [527719]
1-(4-(benzyloxy)phenyl)propan-2-amine Drug Info [529986]
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Drug Info [551346]
1H-Indole-2,3-dione Drug Info [527719]
2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indole Drug Info [526993]
2-(2,4-dichlorophenyl)-4,5-dihydro-1H-imidazole Drug Info [529853]
2-(2-cycloheptylidenehydrazinyl)-4-phenylthiazole Drug Info [551222]
2-(2-cyclohexylidenehydrazinyl)-4-p-tolylthiazole Drug Info [551222]
2-(2-cyclohexylidenehydrazinyl)-4-phenylthiazole Drug Info [551222]
2-(2-cyclopentylidenehydrazinyl)-4-phenylthiazole Drug Info [551222]
2-(3-nitrophenyl)-4,5-dihydro-1H-imidazole Drug Info [529853]
2-(4,5-dihydro-1H-imidazol-2-yl)quinoline Drug Info [529853]
2-(4-chlorophenyl)-4,5-dihydro-1H-imidazole Drug Info [529853]
2-(4-fluorophenyl)-7-methoxy-4H-chromen-4-one Drug Info [530614]
2-(4-methoxyphenyl)-4H-chromene-4-thione Drug Info [530614]
2-(5-phenyl-furan-2-yl)-4,5-dihydro-1H-imidazole Drug Info [528409]
2-(naphthalen-2-yl)-4,5-dihydro-1H-imidazole Drug Info [529853]
2-BFi Drug Info [529853]
2-Bromo-N-(2-morpholinoethyl)nicotinamide Drug Info [530675]
2-Bromo-N-(3-morpholinopropyl)nicotinamide Drug Info [530675]
2-Chloro-N-(2-morpholinoethyl)nicotinamide Drug Info [530675]
2-Chloro-N-(3-morpholinopropyl)nicotinamide Drug Info [530675]
2-Furan-2-yl-4,5-dihydro-1H-imidazole Drug Info [526918]
2-Hydrazino-3-methyl-4(3H)-quinazolinone Drug Info [529873]
2-methyl-9H-indeno[2,1-d]pyrimidin-9-one Drug Info [529077]
2-oxo-N-m-tolyl-2H-chromene-3-carboxamide Drug Info [530001]
2-oxo-N-p-tolyl-2H-chromene-3-carboxamide Drug Info [530001]
2-oxo-N-phenyl-2H-chromene-3-carboxamide Drug Info [530001]
2-p-tolyl-4,5-dihydro-1H-imidazole Drug Info [529853]
2-p-tolyl-4H-chromen-4-one Drug Info [530614]
2-p-tolyl-4H-chromene-4-thione Drug Info [530614]
2-Phenethyl-4,5-dihydro-1H-imidazole Drug Info [526918]
2-Phenoxymethyl-4,5-dihydro-1H-imidazole Drug Info [526918]
2-phenyl-9H-indeno[2,1-d]pyrimidine Drug Info [529077]
2-Phenyl-cyclopropylamine hydrochloride Drug Info [527283]
2-[7-(Benzyloxy)-2-oxo-2H-chromen-4-yl]acetamide Drug Info [530434]
3,4-Benzo-7-(beta-bromoallyloxy)-8-methylcoumarin Drug Info [529735]
3,4-Benzo-7-acetonyloxy-8-methoxycoumarin Drug Info [529735]
3,4-Dichloro-N-(2-methyl-1H-indol-5-yl)benzamide Drug Info [531067]
3-(2-Bromophenyl)-6-methylcoumarin Drug Info [531055]
3-(3-methoxyphenyl)-6-methyl-2H-chromen-2-one Drug Info [530273]
3-(4-hydroxyphenyl)-6-methyl-2H-chromen-2-one Drug Info [530273]
3-(4-methoxyphenyl)-6-methyl-2H-chromen-2-one Drug Info [530273]
3-(phenoxymethyl)-5H-indeno[1,2-c]pyridazin-5-one Drug Info [529077]
3-Chloro-N-(2-methyl-1H-indol-5-yl)benzamide Drug Info [531067]
3-phenyl-9H-indeno[1,2-e][1,2,4]triazin-9-one Drug Info [529077]
4,8-Dimethyl-7-(2'-oxocyclohexyloxy)coumarin Drug Info [529735]
4,9-Dihydro-3H-beta-carboline Drug Info [526994]
4-(2-oxo-2H-chromene-3-carboxamido)benzoic acid Drug Info [530001]
4-(Aminomethyl)-7-(benzyloxy)-2H-chromen-2-one Drug Info [530434]
4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN Drug Info [551374]
4-methyl-7-(2-oxocyclopentyloxy)-2H-chromen-2-one Drug Info [529735]
4-oxo-4H-chromene-3-carboxylic acid Drug Info [530841]
4-phenyl-1,2,3,6-tetrahydropyridine Drug Info [551346]
5-Aminomethyl-3-pyrrol-1-yl-oxazolidin-2-one Drug Info [526287]
5-Bromo-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
5-Bromo-4,9-dihydro-3H-beta-carboline Drug Info [526993]
5-Hydroxy-N-Propargyl-1(R)-Aminoindan Drug Info [551374]
5-Hydroxymethyl-3-pyrrol-1-yl-oxazolidin-2-one Drug Info [526287]
5-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
5-Methoxy-4,9-dihydro-3H-beta-carboline Drug Info [526993]
6-amino-9-methoxy-7H-furo[3,2-g]chromen-7-one Drug Info [529735]
6-Bromo-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
6-Bromo-4,9-dihydro-3H-beta-carboline Drug Info [526993]
6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526994]
6-Methoxy-4,9-dihydro-3H-beta-carboline Drug Info [526994]
7-(3-chlorobenzyloxy)-4-carboxaldehyde-coumarin Drug Info [529080]
7-Acetonyloxy-3,4-cyclohexene-8-methylcoumarin Drug Info [529735]
7-Acetonyloxy-3,4-cyclopentene-8-methylcoumarin Drug Info [529735]
7-Bromo-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
7-Bromo-4,9-dihydro-3H-beta-carboline Drug Info [526993]
7-fluoro-2-(4-fluorophenyl)-4H-chromene-4-thione Drug Info [530614]
7-fluoro-2-(4-methoxyphenyl)-4H-chromen-4-one Drug Info [530614]
7-fluoro-2-p-tolyl-4H-chromen-4-one Drug Info [530614]
7-fluoro-2-p-tolyl-4H-chromene-4-thione Drug Info [530614]
7-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526918]
7-methoxy-2-p-tolyl-4H-chromen-4-one Drug Info [530614]
7-methoxy-2-p-tolyl-4H-chromene-4-thione Drug Info [530614]
7-Methoxy-9H-beta-carboline Drug Info [526993]
7-methyl-2-p-tolyl-4H-chromene-4-thione Drug Info [530614]
8-(3-Bromobenzyloxy)caffeine Drug Info [530647]
8-(3-Chlorobenzyloxy)caffeine Drug Info [530647]
8-(3-Fluorobenzyloxy)caffeine Drug Info [530647]
8-(3-Methoxybenzyloxy)caffeine Drug Info [530647]
8-(3-Methylbenzyloxy)caffeine Drug Info [530647]
8-Benzyloxycaffeine Drug Info [530647]
8-Bromo-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
8-Bromo-4,9-dihydro-3H-beta-carboline Drug Info [526993]
8-Bromo-6-methyl-3-(4'-methoxyphenyl)coumarin Drug Info [531055]
8-Bromo-6-methyl-3-phenylcoumarin Drug Info [531055]
8-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
8-Methoxy-4,9-dihydro-3H-beta-carboline Drug Info [526993]
8-[(3-Trifluoromethyl)benzyloxy]caffeine Drug Info [530647]
9-Methyl-2,3,4,9-tetrahydro-1H-beta-carboline Drug Info [526993]
AS-605240 Drug Info [531046]
Benzyl-methyl-[1-(1H-pyrrol-2-yl)-vinyl]-amine Drug Info [526566]
Butyl-methyl-prop-2-ynyl-amine hydrochloride Drug Info [526820]
C-(1H-Indol-3-yl)-methylamine Drug Info [526993]
CGS-19281A Drug Info [526994]
CHALCONE Drug Info [530087]
CHF-3381 Drug Info [536374]
Cis-2-(4-chlorophenyl)-2-fluorocyclopropanamine Drug Info [529607]
Cis-2-(para-fluorophenyl)cyclopropylamine Drug Info [529607]
Cis-2-Fluoro-2-(4-methoxyphenyl)cyclopropylamine Drug Info [529607]
Cis-2-fluoro-2-phenylcyclopropanamine Drug Info [529607]
Cis-2-phenylcyclopropylamine Drug Info [529607]
CORDOIN Drug Info [530087]
Deprenyl Drug Info [535505]
EVT-301 Drug Info [529908]
Farnesol Drug Info [551374]
Flavin-Adenine Dinucleotide Drug Info [551393]
Heptyl-methyl-prop-2-ynyl-amine hydrochloride Drug Info [526820]
HT-1067 Drug Info [549232]
HYDRAZINECARBOXAMIDE Drug Info [527283]
IPRONIAZIDE Drug Info [530675]
Isatin Drug Info [551391]
Isopropyl-methyl-prop-2-ynyl-amine hydrochloride Drug Info [526820]
Isopsoralen Drug Info [535106]
JD-0100 Drug Info [543639]
L-136662 Drug Info [531046]
Ladostigil Drug Info [531772]
Lauryl Dimethylamine-N-Oxide Drug Info [551393]
Lazabemide Drug Info [534569]
LAZEBEMIDE Drug Info [527719]
Methyl piperate Drug Info [530562]
Methyl-(1,2,3,4-tetrahydro-naphthalen-1-yl)-amine Drug Info [533451]
Methyl-pentyl-prop-2-ynyl-amine oxalic acid Drug Info [526820]
N-(1H-Indol-2-ylmethyl)-N-methyl-N-phenylamine Drug Info [529768]
N-(1H-Indol-2-ylmethyl)-N-phenylamine Drug Info [529768]
N-(2-aminoethyl)-2-oxo-2H-chromene-3-carboxamide Drug Info [530001]
N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE Drug Info [551374]
N-(2-Methyl-1H-indol-5-yl)benzamide Drug Info [531067]
N-(2-Methyl-1H-indol-5-yl)cyclohexanecarboxamide Drug Info [531067]
N-(2-phenylethyl),N-(pyrrol-2-ylmethyl)amine Drug Info [528641]
N-(2-Phenylethyl)-1H-indole-2-carboxamide Drug Info [529768]
N-(3-Phenylpropyl)-1H-indole-2-carboxamide Drug Info [529768]
N-(4-Ethylphenyl)-2-oxo-2H-chromene-3-carboxamide Drug Info [530001]
N-(4-Phenylbutyl)-1H-indole-2-carboxamide Drug Info [529768]
N-(benzyl),N-(pyrrol-2-ylmethyl)amine Drug Info [528641]
N-(propargyl),N-(pyrrol-2-ylmethyl)amine Drug Info [528641]
N-Benzyl,N-methyl-1H-indole-2-carboxamide Drug Info [529768]
N-Benzyl-1H-indole-2-carboxamide Drug Info [529768]
N-benzyl-2-oxo-2H-chromene-3-carboxamide Drug Info [530001]
N-Benzyl-N-(1H-indol-2-ylmethyl)-N-methylamine Drug Info [529768]
N-cyclohexyl-2-oxo-2H-chromene-3-carboxamide Drug Info [530001]
N-isobutyl-2-oxo-2H-chromene-3-carboxamide Drug Info [530001]
N-methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine Drug Info [528641]
N-methyl,N-(propargyl),N-(pyrrol-2-ylmethyl)amine Drug Info [528641]
N-Methyl,N-phenyl-1H-indole-2-carboxamide Drug Info [529768]
N-Methyl-N-phenyl-2-oxo-2H-chromene-3-carboxamide Drug Info [530001]
N-Methyl-N-Propargyl-1(R)-Aminoindan Drug Info [551374]
N-Phenyl-1H-indole-2-carboxamide Drug Info [529768]
N-Propargyl-1(S)-Aminoindan Drug Info [551374]
N2-[4-(benzyloxy)benzyl]glycinamide Drug Info [529025]
N2-{4-[(3-chlorobenzyl)oxy]benzyl}glycinamide Drug Info [529025]
N2-{4-[(3-fluorobenzyl)oxy]benzyl}glycinamide Drug Info [529025]
N2-{4-[(4-chlorobenzyl)oxy]benzyl}glycinamide Drug Info [529025]
N2-{4-[(4-nitrobenzyl)oxy]benzyl}glycinamide Drug Info [529025]
NSC-50187 Drug Info [530614]
NSC-50393 Drug Info [530614]
NSC-93405 Drug Info [530614]
NW-1772 Drug Info [543639]
P2B-001 Drug Info [528670]
Pargyline Drug Info [537499]
PF9601N Drug Info [536923]
Phenelzine Drug Info [536743]
Phenyl 4-(4,5-dihydro-1H-imidazol-2-yl)benzoate Drug Info [529853]
PIPERINE Drug Info [530562]
PNU-22394 Drug Info [526993]
Psoralen Drug Info [535106]
Rasagiline Drug Info [537470]
RS-1636 Drug Info [535422]
RS-1653 Drug Info [535422]
RWJ-416457 Drug Info [543639]
Safinamide Drug Info [536266], [536498]
Selegiline Drug Info [543639]
SKL-PD Drug Info [543639]
SL-25.1188 Drug Info [530356]
TOLOXATONE Drug Info [526287]
TRACIZOLINE Drug Info [526918]
Trans-2-(4-chlorophenyl)-2-fluorocyclopropanamine Drug Info [529607]
Trans-2-fluoro-2-(4-fluorophenyl)cyclopropanamine Drug Info [529607]
Trans-2-fluoro-2-p-tolylcyclopropanamine Drug Info [529607]
Trans-2-fluoro-2-phenylcyclopropylamin Drug Info [529607]
Tranylcypromine Drug Info [536265], [537851]
TRYPTAMINE Drug Info [526993]
TRYPTOLINE Drug Info [526918]
VAR-10300 Drug Info [543639]
Zydis selegiline Drug Info [536266]
[(1e)-4-Phenylbut-1-Enyl]Benzene Drug Info [551374]
Modulator 4-fluoroselegiline Drug Info [533786]
Indeloxazine Drug Info [551871]
LU-53439 Drug Info
Milacemide Drug Info [530942]
MOFEGILINE Drug Info [529842]
Neu-120 Drug Info
RG1577 Drug Info [550238]
Selegiline Hydrochloride Drug Info [556264]
VAR-10200 Drug Info [543639]
Antagonist 4-Methoxyamphetamine Drug Info [551380]
MMDA Drug Info [551393]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
TEP EXP Info
Pathways
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Dopamine degradation
Putrescine degradation III
Noradrenaline and adrenaline degradation
KEGG Pathway Glycine, serine and threonine metabolism
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Drug metabolism - cytochrome P450
Metabolic pathways
Serotonergic synapse
Dopaminergic synapse
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine degredation
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
WikiPathways Tryptophan metabolism
Dopamine metabolism
Phase 1 - Functionalization of compounds
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