Drug General Information
Drug ID	D0D2YR
Former ID	DNC011605
Drug Name	9-Methyl-2,3,4,9-tetrahydro-1H-beta-carboline
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526993]
Structure		Download 2D MOL 3D MOL
Formula	C12H14N2
Canonical SMILES	CN1C2=C(CCNC2)C3=CC=CC=C31
InChI	1S/C12H14N2/c1-14-11-5-3-2-4-9(11)10-6-7-13-8-12(10)14/h2-5,13H,6-8H2,1H3
InChIKey	STMNLEHELVDDKF-UHFFFAOYSA-N
PubChem Compound ID	10997754
Target and Pathway
Target(s)	Amine oxidase [flavin-containing] A	Target Info	Inhibitor	[526993]
	Amine oxidase [flavin-containing] B	Target Info	Inhibitor	[526993]
BioCyc Pathway	Superpathway of tryptophan utilization
	Dopamine degradation
	Putrescine degradation III
	Noradrenaline and adrenaline degradation
	Serotonin degradation
	Superpathway of melatonin degradation
	Melatonin degradation IIPWY66-401:Superpathway of tryptophan utilization
	Tryptophan degradation via tryptamine
KEGG Pathway	Glycine, serine and threonine metabolism
	Arginine and proline metabolism
	Histidine metabolism
	Tyrosine metabolism
	Phenylalanine metabolism
	Tryptophan metabolism
	Drug metabolism - cytochrome P450
	Metabolic pathways
	Serotonergic synapse
	Dopaminergic synapse
	Cocaine addiction
	Amphetamine addiction
	Alcoholismhsa00260:Glycine, serine and threonine metabolism
	Alcoholism
NetPath Pathway	IL4 Signaling Pathway
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	5-Hydroxytryptamine degredation
	Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
	Dopamine receptor mediated signaling pathway
Pathway Interaction Database	Alpha-synuclein signaling
PathWhiz Pathway	Histidine Metabolism
	Tyrosine Metabolism
	Glycine and Serine Metabolism
Reactome	Norepinephrine Neurotransmitter Release Cycle
WikiPathways	SIDS Susceptibility Pathways
	Biogenic Amine Synthesis
	Oxidative Stress
	Dopamine metabolism
	Phase 1 - Functionalization of compounds
	Neurotransmitter Release Cycle
	Neurotransmitter Clearance In The Synaptic Cleft
	Serotonin Transporter ActivityWP465:Tryptophan metabolism
References
Ref 526993	Bioorg Med Chem Lett. 2004 Feb 23;14(4):999-1002.Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation.
Ref 526993	Bioorg Med Chem Lett. 2004 Feb 23;14(4):999-1002.Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.