Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0TV6I
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| Former ID |
DCL000972
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| Drug Name |
Safinamide
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| Synonyms |
Fce 26743; M6252; Fce-26743; N2-{4-[(3-fluorobenzyl)oxy]benzyl}-L-alaninamide; (2R)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide; (2S)-2-[[4-[(3-Fluorophenyl)methoxy]phenyl]methylamino]propanamide; (S)-2-(((4-((3-Fluorophenyl)methoxy)phenyl)methyl)amino)propanamide; 2-(4-(3-Fluorobenzyloxy)benzylamino)propionamide
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| Drug Type |
Small molecular drug
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| Company |
Us Worldmeds
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| Structure |
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Download2D MOL |
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| Formula |
C17H19FN2O2
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| InChI |
InChI=1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1
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| InChIKey |
NEMGRZFTLSKBAP-LBPRGKRZSA-N
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| CAS Number |
CAS 133865-89-1
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| PubChem Compound ID | |||||
| PubChem Substance ID |
14825333, 14849630, 23920185, 26737944, 29309988, 46519220, 76856311, 93309595, 103526952, 103971166, 104375653, 124766868, 126651862, 128690685, 134338858, 134339406, 134339529, 135087308, 135626876, 137027831, 143315332, 152258889, 160826164, 162223650, 163092722, 163388329, 163686465, 163840927, 174006265, 174527236, 184816720, 196108862, 196409670, 198984441, 198991902, 204430311, 223621328, 223711810, 224284738, 226449995, 241032188, 249855421, 250205029, 252078194, 252166503, 252431202, 252494053
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| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] B | Target Info | Inhibitor | [536266], [536498] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| Pathway Interaction Database | Alpha-synuclein signaling | ||||
| References | |||||
| Ref 536923 | Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42. | ||||
| Ref 543044 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8291). | ||||
| Ref 889446 | Drugs@FDA (Edaravone) | ||||
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