Drug General Information
Drug ID	D0J2MJ
Drug Name	Selegiline Hydrochloride
Synonyms	Eldepryl; Selegiline Hydrochloride; Zelapar; Eldepryl; Jumex
Drug Type	Small molecular drug
Indication	Parkinson's disease [ICD9: 332; ICD10:G20]		Approved	[551871]
Therapeutic Class	Neurology Agents
Company	Somerset Pharmaceuticals Inc
Structure		Download 2D MOL 3D MOL
Formula	C13H18ClN
PubChem Compound ID	26758
Target and Pathway
Target(s)	Amine oxidase [flavin-containing] B	Target Info	Modulator	[556264]
BioCyc Pathway	Superpathway of tryptophan utilization
	Tryptophan degradation via tryptamine
	Dopamine degradation
	Putrescine degradation III
	Noradrenaline and adrenaline degradation
KEGG Pathway	Glycine, serine and threonine metabolism
	Arginine and proline metabolism
	Histidine metabolism
	Tyrosine metabolism
	Phenylalanine metabolism
	Tryptophan metabolism
	Drug metabolism - cytochrome P450
	Metabolic pathways
	Serotonergic synapse
	Dopaminergic synapse
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	5-Hydroxytryptamine degredation
	Dopamine receptor mediated signaling pathway
Pathway Interaction Database	Alpha-synuclein signaling
WikiPathways	Tryptophan metabolism
	Dopamine metabolism
	Phase 1 - Functionalization of compounds
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 556264	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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