Drug Information
Drug General Information | |||||
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Drug ID |
D0J2MJ
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Drug Name |
Selegiline Hydrochloride
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Synonyms |
Eldepryl; Selegiline Hydrochloride; Zelapar; Eldepryl; Jumex
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Drug Type |
Small molecular drug
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Indication | Parkinson's disease [ICD9: 332; ICD10:G20] | Approved | [1] | ||
Therapeutic Class |
Neurology Agents
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Company |
Somerset Pharmaceuticals Inc
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Structure |
Download2D MOL |
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Formula |
C13H18ClN
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Amine oxidase [flavin-containing] B | Target Info | Modulator | [2] | |
BioCyc Pathway | Superpathway of tryptophan utilization | ||||
Tryptophan degradation via tryptamine | |||||
Dopamine degradation | |||||
Putrescine degradation III | |||||
Noradrenaline and adrenaline degradation | |||||
KEGG Pathway | Glycine, serine and threonine metabolism | ||||
Arginine and proline metabolism | |||||
Histidine metabolism | |||||
Tyrosine metabolism | |||||
Phenylalanine metabolism | |||||
Tryptophan metabolism | |||||
Drug metabolism - cytochrome P450 | |||||
Metabolic pathways | |||||
Serotonergic synapse | |||||
Dopaminergic synapse | |||||
Cocaine addiction | |||||
Amphetamine addiction | |||||
Alcoholism | |||||
PANTHER Pathway | Adrenaline and noradrenaline biosynthesis | ||||
5-Hydroxytryptamine degredation | |||||
Dopamine receptor mediated signaling pathway | |||||
Pathway Interaction Database | Alpha-synuclein signaling | ||||
WikiPathways | Tryptophan metabolism | ||||
Dopamine metabolism | |||||
Phase 1 - Functionalization of compounds | |||||
References | |||||
REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | ||||
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