Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0S2UG
|
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| Former ID |
DIB004250
|
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| Drug Name |
Selegiline
|
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| Synonyms |
Selegiline (transdermal, Parkinson's/depression)
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| Drug Type |
Small molecular drug
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| Company |
Syntropharma
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| Structure |
|
Download2D MOL |
|||
| Formula |
C13H17N
|
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| InChI |
InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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| InChIKey |
MEZLKOACVSPNER-GFCCVEGCSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9454, 7980587, 8169367, 11113910, 11466580, 11467700, 11486280, 14772861, 14797266, 17397820, 26752066, 29293584, 46509459, 47662432, 47810884, 48259382, 48259383, 48334634, 48416534, 49698549, 49880108, 50104720, 50104721, 50139277, 53789537, 57310317, 61127936, 80766630, 85787938, 85788262, 89449661, 92308745, 92310005, 94569169, 99300917, 103252336, 104298196, 104829538, 117391911, 117884350, 128586172, 134337870, 134339187, 134989154, 137001242, 142170639, 160964372, 175267457, 176484098, 176484773
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| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] B | Target Info | Inhibitor | [543639] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| Pathway Interaction Database | Alpha-synuclein signaling | ||||
| References | |||||
| Ref 522265 | ClinicalTrials.gov (NCT00640159) Tolerability and Efficacy of Switch From Oral Selegiline to Orally Disintegrating Selegiline (Zelapar) in Patients With Parkinson's Disease. U.S. National Institutes of Health. | ||||
| Ref 541748 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6639). | ||||
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