Drug General Information
Drug ID	D0A4IY
Former ID	DNC005391
Drug Name	HYDRAZINECARBOXAMIDE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527283]
Structure		Download 2D MOL 3D MOL
Formula	CH5N3O
Canonical SMILES	C(=O)(N)NN
InChI	1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)
InChIKey	DUIOPKIIICUYRZ-UHFFFAOYSA-N
PubChem Compound ID	5196
Target and Pathway
Target(s)	Amine oxidase [flavin-containing] A	Target Info	Inhibitor	[527283]
	Amine oxidase [flavin-containing] B	Target Info	Inhibitor	[527283]
BioCyc Pathway	Superpathway of tryptophan utilization
	Dopamine degradation
	Putrescine degradation III
	Noradrenaline and adrenaline degradation
	Serotonin degradation
	Superpathway of melatonin degradation
	Melatonin degradation IIPWY66-401:Superpathway of tryptophan utilization
	Tryptophan degradation via tryptamine
KEGG Pathway	Glycine, serine and threonine metabolism
	Arginine and proline metabolism
	Histidine metabolism
	Tyrosine metabolism
	Phenylalanine metabolism
	Tryptophan metabolism
	Drug metabolism - cytochrome P450
	Metabolic pathways
	Serotonergic synapse
	Dopaminergic synapse
	Cocaine addiction
	Amphetamine addiction
	Alcoholismhsa00260:Glycine, serine and threonine metabolism
	Alcoholism
NetPath Pathway	IL4 Signaling Pathway
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	5-Hydroxytryptamine degredation
	Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
	Dopamine receptor mediated signaling pathway
Pathway Interaction Database	Alpha-synuclein signaling
PathWhiz Pathway	Histidine Metabolism
	Tyrosine Metabolism
	Glycine and Serine Metabolism
Reactome	Norepinephrine Neurotransmitter Release Cycle
WikiPathways	SIDS Susceptibility Pathways
	Biogenic Amine Synthesis
	Oxidative Stress
	Dopamine metabolism
	Phase 1 - Functionalization of compounds
	Neurotransmitter Release Cycle
	Neurotransmitter Clearance In The Synaptic Cleft
	Serotonin Transporter ActivityWP465:Tryptophan metabolism
References
Ref 527283	J Med Chem. 2004 Nov 18;47(24):5860-71.Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.
Ref 527283	J Med Chem. 2004 Nov 18;47(24):5860-71.Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.

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