Drug General Information
Drug ID	D08DWH
Former ID	DIB007449
Drug Name	Idrapril
Synonyms	LG-32001
Drug Type	Small molecular drug
Indication	Hypertension [ICD9: 401; ICD10:I10-I16]		Discontinued in Phase 2	[545074]
Company	Laboratorio Guidotti SpA
Structure		Download 2D MOL 3D MOL
Formula	C11H18N2O5
Canonical SMILES	C(=O)([C@H]1[C@@H](C(=O)O)CCCC1)N(CC(=O)NO)C
CAS Number	CAS 127420-24-0
PubChem Compound ID	65960
Target and Pathway
Target(s)	Angiotensin-converting enzyme	Target Info	Inhibitor	[526807]
KEGG Pathway	Renin-angiotensin system
	Chagas disease (American trypanosomiasis)
	Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway	Angiotensin Metabolism
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	ACE Inhibitor Pathway
	Metabolism of Angiotensinogen to Angiotensins
References
Ref 545074	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002045)
Ref 526807	Pharmacology of idrapril: a new class of angiotensin converting enzyme inhibitors. J Cardiovasc Pharmacol. 1992 Jul;20(1):139-46.

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