Drug Information

Drug General Information
Drug ID
D08LMS
Former ID
DNCL002662
Drug Name
CG201
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [547378]
Company
CG Therapeutics
Structure
Download
2D MOL

3D MOL
Formula
C23H31NO7S
Canonical SMILES
C[N+]1(CCCCC1COC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.COS(<br />=O)(=O)[O-]
InChI
1S/C22H28NO3.CH4O4S/c1-23(2)16-10-9-15-20(23)17-26-21(24)22(25,18-11-5-3-6-12-18)19-13-7-4-8-14-19;1-5-6(2,3)4/h3-8,11-14,20,25H,9-10,15-17H2,1-2H3;1H3,(H,2,3,4)/q+1;/p-1
InChIKey
AXKJGGRSAVLXTE-UHFFFAOYSA-M
PubChem Compound ID
31799
PubChem Substance ID
7848595, 8172392, 15380742, 34673897, 50017655, 57311295, 79633392, 84940866, 104311837, 125386406, 134994347, 135029968, 144205980, 160698138, 162074820, 163133021, 164836690, 186000983, 226413205
Target and Pathway
Target(s) Gonadotropin-releasing hormone Target Info Modulator [1572591]
KEGG Pathway GnRH signaling pathway
Pathway Interaction Database Nongenotropic Androgen signaling
Reactome Hormone ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 547378Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015700)
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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