Drug General Information
Drug ID
D0A5EN
Former ID
DCL000694
Drug Name
AMG-714
Drug Type
Antibody
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Discontinued in Phase 1 [536651]
Company
Genmab; Amgen
Target and Pathway
Target(s) Interleukin-15 Target Info [536651]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
TNF signaling pathway
Intestinal immune network for IgA production
HTLV-I infection
Herpes simplex infection
Rheumatoid arthritis
NetPath Pathway TCR Signaling Pathway
FSH Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
WikiPathways Cytokines and Inflammatory Response
References
Ref 536651Emerging drugs for rheumatoid arthritis. Expert Opin Emerg Drugs. 2008 Mar;13(1):175-96.
Ref 536651Emerging drugs for rheumatoid arthritis. Expert Opin Emerg Drugs. 2008 Mar;13(1):175-96.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.