Drug Information

Drug General Information
Drug ID
D0GV9Q
Former ID
DNC002603
Drug Name
N-Formylmethionine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C6H11NO3S
Canonical SMILES
CSCCC(C(=O)O)NC=O
InChI
1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChIKey
PYUSHNKNPOHWEZ-YFKPBYRVSA-N
PubChem Compound ID
439750
PubChem Substance ID
6033, 10298452, 16532964, 36883922, 46505840, 49742586, 57403163, 76191993, 85239783, 85244536, 87569918, 92297514, 104621308, 118314016, 128987974, 134932038, 137007330, 138672551, 144220628, 160797390, 160967478, 162528723, 163410064, 163632921, 164831445, 172860544, 185995338, 198977122, 204363658, 204938103, 219400602, 223535772, 223940100, 226424107, 241085784, 246681219, 249855625, 249926568, 250214585, 252070628, 252142044, 252314189, 252412016, 252547013
Target and Pathway
Target(s) Glutamate--cysteine ligase regulatorysubunit Target Info Inhibitor [551393]
Antithrombin-III Target Info Inhibitor [551393]
NADH dehydrogenase Target Info Inhibitor [551393]
KEGG Pathway Glutathione metabolism
Metabolic pathwayshsa04610:Complement and coagulation cascadeshsa00190:Oxidative phosphorylation
Metabolic pathways
Parkinson's disease
PANTHER Pathway Blood coagulation
Pathway Interaction Database Glypican 1 network
PathWhiz Pathway Glutamate Metabolism
Glutathione Metabolism
Cysteine Metabolism
Reactome Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
WikiPathways Transcriptional activation by NRF2
NRF2 pathway
Nuclear Receptors Meta-Pathway
Metabolism of amino acids and derivatives
Trans-sulfuration and one carbon metabolism
Trans-sulfuration pathway
Phase II conjugation
Glutathione metabolismWP558:Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)WP623:Oxidative phosphorylation
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Electron Transport Chain
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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