Drug Information

Drug General Information
Drug ID
D0H2YT
Former ID
DNC002715
Drug Name
Inosinic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468189]
Structure
Download
2D MOL

3D MOL
Formula
C10H13N4O8P
InChI
InChI=1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKey
GRSZFWQUAKGDAV-KQYNXXCUSA-N
CAS Number
CAS 131-99-7
PubChem Compound ID
8582
PubChem Substance ID
3430, 820101, 820531, 820670, 820681, 823691, 824841, 826549, 826551, 829137, 829142, 831000, 834259, 834953, 835063, 835066, 835070, 835836, 835854, 3725895, 7888381, 8025323, 8028013, 8028199, 8145617, 14720270, 14876084, 14945206, 24697872, 25636028, 26702341, 26705921, 26705926, 26736201, 29227253, 46391985, 46392844, 46392845, 46393007, 46393652, 46393705, 49655337, 49985039, 50086997, 50087003, 57325113, 57580794, 57580820, 57580825, 80693911
Target and Pathway
Target(s) Inosine-5'-monophosphate dehydrogenase 2 Target Info Inhibitor [551393]
Inosine-5'-monophosphate dehydrogenase Target Info Inhibitor [551393]
Glycogen phosphorylase, muscle form Target Info Inhibitor [551393]
Hypoxanthine-guanine phosphoribosyltransferase Target Info Inhibitor [551393]
Adenylosuccinate synthetase Target Info Inhibitor [551393]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides de novo biosynthesis
Superpathway of purine nucleotide salvage
Purine nucleotides de novo biosynthesis
Guanosine ribonucleotides de novo biosynthesisPWY-5941:Glycogenolysis
KEGG Pathway Purine metabolism
Drug metabolism - other enzymes
Metabolic pathwayshsa00500:Starch and sucrose metabolism
Metabolic pathways
Insulin signaling pathway
Glucagon signaling pathwayhsa00230:Purine metabolism
PANTHER Pathway De novo purine biosynthesisP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Purine Metabolism
Reactome Purine ribonucleoside monophosphate biosynthesisR-HSA-74217:Purine salvage
WikiPathways Glycogen Metabolism
Metabolism of carbohydratesWP404:Nucleotide Metabolism
Mesodermal Commitment Pathway
Endoderm Differentiation
Metabolism of nucleotides
References
Ref 468189(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5124).
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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