TTD | Drug: D0IK4V

Drug General Information
Drug ID	D0IK4V
Former ID	DNC011348
Drug Name	GNF-PF-5134
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531262]
Structure		Download 2D MOL 3D MOL
Formula	C17H20N2
Canonical SMILES	CCN1C2=CC=CC=C2N(C1(C)C3=CC=CC=C3)C
InChI	1S/C17H20N2/c1-4-19-16-13-9-8-12-15(16)18(3)17(19,2)14-10-6-5-7-11-14/h5-13H,4H2,1-3H3
InChIKey	QWPMTQMHWWDYRA-UHFFFAOYSA-N
PubChem Compound ID	3124417
Target and Pathway
Target(s)	Induced myeloid leukemia cell differentiation protein Mcl-1	Target Info	Inhibitor	[531262]
Target(s)	Mannose-6-phosphate isomerase	Target Info	Inhibitor	[531262]
KEGG Pathway	PI3K-Akt signaling pathway
KEGG Pathway	MicroRNAs in cancer
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	Apoptosis signaling pathway
PANTHER Pathway	CCKR signaling map ST
Pathway Interaction Database	E2F transcription factor network
	Direct p53 effectors
	IL6-mediated signaling events
	HIF-1-alpha transcription factor network
WikiPathways	Apoptosis
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	miR-targeted genes in leukocytes - TarBase
	Apoptosis Modulation and Signaling
References
Ref 531262	Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262	Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

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Drug Information