Drug Information

Drug General Information
Drug ID
D0JA5D
Former ID
DIB020834
Drug Name
RO330-0802/001
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542838]
Structure
Download
2D MOL
Formula
C27H30Cl2N4O3S
InChI
InChI=1S/C27H30Cl2N4O3S/c1-35-24-6-4-19(12-25(24)36-2)20-14-32-27(33-15-20)37-16-26(34)30-8-7-21-10-18(13-31-21)9-17-3-5-22(28)23(29)11-17/h3-6,11-12,14-15,18,21,31H,7-10,13,16H2,1-2H3,(H,30,34)/t18-,21-/m1/s1
InChIKey
OPLAETMHSJFRBS-WIYYLYMNSA-N
PubChem Compound ID
10304110
PubChem Substance ID
15335048, 22677744, 41369953, 75293039, 135650916, 140114267, 140325528, 227456461, 244808941
Target and Pathway
Target(s) mRNA of CCR3 chemokine Target Info Antagonist [526363]
NetPath Pathway IL3 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
References
Ref 542838(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 792).
Ref 526363Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med. 2002 Jun 15;165(12):1602-9.

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