Drug Information

Drug General Information
Drug ID
D0L3IL
Former ID
DNCL002022
Drug Name
ASM8
Drug Type
Antisense drug
Indication Allergic asthma [ICD9: 493, 995.3; ICD10:J45, T78.4] Phase 2 [523524]
Company
Pharmaxis
Target and Pathway
Target(s) mRNA of CCR3 chemokine Target Info [543892]
NetPath Pathway IL3 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
References
Ref 523524ClinicalTrials.gov (NCT01380236) A Single Blind Study to Evaluate the Safety, Tolerability and Explore the Efficacy of 8.0 mg ASM8 Inhaled Daily for 14 Days in Severe Asthma. U.S. National Institutesof Health.
Ref 543892(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 60).

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