Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0NN7D
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| Former ID |
DNC000037
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| Drug Name |
19-nor-10-azasteroid skeleton
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C10H13BrN6O3
|
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| Canonical SMILES |
C1=NC2=C(C(=N1)N)C(=NN2C3C(C(C(O3)CN)O)O)Br
|
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| InChI |
1S/C10H13BrN6O3/c11-7-4-8(13)14-2-15-9(4)17(16-7)10-6(19)5(18)3(1-12)20-10/h2-3,5-6,10,18-19H,1,12H2,(H2,13,14,15)/t3-,5-,6-,10-/m1/s1
|
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| InChIKey |
LTTBFVDMHCIDPM-BHBWVORQSA-N
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| CAS Number |
CAS 144928-48-3
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Target Info | Inhibitor | [1] | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Superpathway of steroid hormone biosynthesis | ||||
| Allopregnanolone biosynthesis | |||||
| Androgen biosynthesisPWY-7305:Superpathway of steroid hormone biosynthesis | |||||
| Androgen biosynthesis | |||||
| KEGG Pathway | Steroid hormone biosynthesis | ||||
| Prostate cancerhsa00140:Steroid hormone biosynthesis | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Reactome | Androgen biosynthesisR-HSA-193048:Androgen biosynthesis | ||||
| References | |||||
| REF 1 | 19-nor-10-azasteroids: a novel class of inhibitors for human steroid 5alpha-reductases 1 and 2. J Med Chem. 1997 Mar 28;40(7):1112-29. | ||||
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