Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O1AV
|
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| Former ID |
DIB006186
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| Drug Name |
Squalestatin 1
|
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| Synonyms |
Zaragozic acid A; Squalestatin 1, Glaxo; Zaragozic acid A, Glaxo
|
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| Drug Type |
Small molecular drug
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| Company |
Glaxo Wellcome plc
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| Structure |
|
Download2D MOL |
|||
| Formula |
C35H46O14
|
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| InChI |
InChI=1S/C35H46O14/c1-7-19(2)17-20(3)13-14-25(37)47-28-27(38)33(48-29(30(39)40)34(45,31(41)42)35(28,49-33)32(43)44)16-15-21(4)26(46-23(6)36)22(5)18-24-11-9-8-10-12-24/h8-14,19-20,22,26-29,38,45H,4,7,15-18H2,1-3,5-6H3,(H,39,40)(H,41,42)(H,43,44)/b14-13+/t19-,20+,22+,26+,27+,28+,29+,33-,34+,35-/m0/s1
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| InChIKey |
DFKDOZMCHOGOBR-NCSQYGPNSA-N
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| CAS Number |
CAS 142561-96-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
611432, 648586, 11968042, 14937429, 43031363, 50070494, 50071135, 53788696, 57368011, 78965650, 92764885, 103204732, 103948803, 114555911, 134348391, 135077136, 135631679, 135631683, 135642575, 135652728, 137103450, 162224515, 163835607, 179149915, 198947077, 208012623, 208012697, 226736445, 241180785
|
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| Target and Pathway | |||||
| Target(s) | Squalene synthetase | Target Info | Modulator | [527638] | |
| PANTHER Pathway | Cholesterol biosynthesis | ||||
| PathWhiz Pathway | Steroid Biosynthesis | ||||
| References | |||||
| Ref 540059 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3057). | ||||
| Ref 545281 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002681) | ||||
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