Drug Information

Drug General Information
Drug ID
D0O4ZX
Former ID
DIB000999
Drug Name
Encapsulated cells
Synonyms
CapCell; Encapsulated cells (CYP2B1 secreting); Encapsulated cells (CYP2B1 secreting), Bavarian Nordic; Encapsulated cells/ifosfamide, Bavarian Nordic; Gene therapy (encapsulated cells/breast cancer/pancreatic cancer), Bavarian Nordic
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Discontinued in Phase 2 [546933]
Company
Bavarian Nordic A/S
Target and Pathway
Target(s) Cytochrome P450 reductase Target Info Modulator [527680]
BioCyc Pathway Superpathway of tryptophan utilization
Superpathway of melatonin degradation
Melatonin degradation I
Vitamin D<sub>3</sub> biosynthesis
Bile acid biosynthesis, neutral pathway
WikiPathways Oxidation by Cytochrome P450
References
Ref 546933Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011277)
Ref 527680Peritoneal cancer treatment with CYP2B1 transfected, microencapsulated cells and ifosfamide. Cancer Gene Ther. 2006 Jan 1;13(1):65-73.

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