TTD | Drug: D0Q2OK

Drug General Information
Drug ID	D0Q2OK
Former ID	DIB020436
Drug Name	MRS2693
Synonyms	MRS-2693; MRS 2693; 5-iodo-uridine-5'-diphosphate; 5-iodo-UDP
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539098]
Structure		Download 2D MOL
Formula	C9H13IN2O12P2
InChI	InChI=1S/C9H13IN2O12P2/c10-4-1-5(13)11-9(16)12(4)8-7(15)6(14)3(23-8)2-22-26(20,21)24-25(17,18)19/h1,3,6-8,14-15H,2H2,(H,20,21)(H,11,13,16)(H2,17,18,19)/t3-,6-,7-,8-/m1/s1
InChIKey	ZPKIYZBENSTKTC-YXZULKJRSA-N
PubChem Compound ID	44415771
PubChem Substance ID	104076483, 135650663, 242110701
Target and Pathway
Target(s)	P2Y purinoceptor 6	Target Info	Agonist	[528405]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
Reactome	P2Y receptors
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539098	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1747).
Ref 528405	Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J Med Chem. 2006 Sep 7;49(18):5532-43.

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Drug Information