Drug General Information
Drug ID
D0Q9WN
Former ID
DIB004911
Drug Name
FC EPO
Synonyms
Long acting erythropoietin (anemia), Merck Serono
Indication Anemia [ICD9: 280-285; ICD10:D50-D64] Discontinued in Phase 1 [548647]
Company
Merck Serono SA
Target and Pathway
Target(s) Erythropoietin ligand Target Info Agonist [531957]
KEGG Pathway Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Pathway Interaction Database HIF-2-alpha transcription factor network
Signaling events mediated by Stem cell factor receptor (c-Kit)
EPO signaling pathway
HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
WikiPathways EPO Receptor Signaling
Hematopoietic Stem Cell Differentiation
Differentiation Pathway
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
References
Ref 548647Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027346)
Ref 531957Detection of EPO-Fc fusion protein in human blood: screening and confirmation protocols for sports drug testing. Drug Test Anal. 2012 Nov;4(11):818-29.

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