Drug General Information
Drug ID	D0R8TH
Former ID	DNC007033
Drug Name	(RS/SR)-2-[1-(4-chlorophenyl)propyl]piperidine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528619]
Structure		Download 2D MOL 3D MOL
Formula	C14H20ClN
Canonical SMILES	CCC(C1CCCCN1)C2=CC=C(C=C2)Cl
InChI	1S/C14H20ClN/c1-2-13(14-5-3-4-10-16-14)11-6-8-12(15)9-7-11/h6-9,13-14,16H,2-5,10H2,1H3
InChIKey	CJUVIUZOUUBMJB-UHFFFAOYSA-N
PubChem Compound ID	16102750
Target and Pathway
Target(s)	Sodium-dependent dopamine transporter	Target Info	Inhibitor	[528619]
KEGG Pathway	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	Parkinson disease
	Dopamine receptor mediated signaling pathway
Pathway Interaction Database	Alpha-synuclein signaling
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Dopaminergic Neurogenesis
	Parkinsons Disease Pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
	Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 528619	J Med Chem. 2007 Jan 25;50(2):219-32.Slow-onset, long-duration, alkyl analogues of methylphenidate with enhanced selectivity for the dopamine transporter.
Ref 528619	J Med Chem. 2007 Jan 25;50(2):219-32.Slow-onset, long-duration, alkyl analogues of methylphenidate with enhanced selectivity for the dopamine transporter.

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