Drug General Information
Drug ID	D0T1QV
Former ID	DNCL002941
Drug Name	ARA 290
Indication	Depression; Diabetic neuropathy; Mood disorder [ICD9: 311, 250, 250.6, 356.0, 356.8; ICD10:F30-F39, E11.40]		Phase 2	[549308]
Company	Araim Pharmaceuticals
Structure		Download 2D MOL
Target and Pathway
Target(s)	Erythropoietin ligand	Target Info	Modulator
KEGG Pathway	Cytokine-cytokine receptor interaction
	HIF-1 signaling pathway
	PI3K-Akt signaling pathway
	Jak-STAT signaling pathway
	Hematopoietic cell lineage
Pathway Interaction Database	HIF-2-alpha transcription factor network
	Signaling events mediated by Stem cell factor receptor (c-Kit)
	EPO signaling pathway
	HIF-1-alpha transcription factor network
Reactome	Regulation of gene expression by Hypoxia-inducible Factor
WikiPathways	EPO Receptor Signaling
	Hematopoietic Stem Cell Differentiation
	Differentiation Pathway
	Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
References
Ref 549308	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035038)

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