Drug General Information
Drug ID
D0T4UE
Former ID
DNC009571
Drug Name
Mycophenolic bis(sulfonamide)
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529565]
Structure
Download
2D MOL

3D MOL

Formula
C13H18N2O8S2
Canonical SMILES
CC1=C(C(=C(C2=C1COC2=O)O)CCNS(=O)(=O)CS(=O)(=O)N)OC
InChI
1S/C13H18N2O8S2/c1-7-9-5-23-13(17)10(9)11(16)8(12(7)22-2)3-4-15-25(20,21)6-24(14,18)19/h15-16H,3-6H2,1-2H3,(H2,14,18,19)
InChIKey
IVAOVFUEHDFBPQ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Inosine-5'-monophosphate dehydrogenase 2 Target Info Inhibitor [529565]
Inosine-5'-monophosphate dehydrogenase 1 Target Info Inhibitor [529565]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides de novo biosynthesis
Superpathway of purine nucleotide salvage
Purine nucleotides de novo biosynthesis
Guanosine ribonucleotides de novo biosynthesisPWY-6353:Purine nucleotides degradation
Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway Purine metabolism
Drug metabolism - other enzymes
Metabolic pathwayshsa00230:Purine metabolism
Metabolic pathways
PANTHER Pathway De novo purine biosynthesis
PathWhiz Pathway Purine Metabolism
Reactome Purine ribonucleoside monophosphate biosynthesisR-HSA-73817:Purine ribonucleoside monophosphate biosynthesis
WikiPathways Nucleotide Metabolism
References
Ref 529565Bioorg Med Chem. 2008 Aug 1;16(15):7462-9. Epub 2008 Jun 10.Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.
Ref 529565Bioorg Med Chem. 2008 Aug 1;16(15):7462-9. Epub 2008 Jun 10.Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.