Drug General Information
Drug ID
D0U7QA
Former ID
DNC002533
Drug Name
Pyroglutamic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467944]
Structure
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2D MOL

3D MOL

Formula
C5H7NO3
InChI
InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)
InChIKey
ODHCTXKNWHHXJC-UHFFFAOYSA-N
CAS Number
CAS 98-79-3
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Pancreatic alpha-amylase Target Info Inhibitor [551393]
Angiogenin Target Info Inhibitor [551393]
Orexin Target Info Inhibitor [551393]
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome Adherens junctions interactionsR-HSA-416476:G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 467944(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4703).
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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