Drug General Information
Drug ID
D0VD5N
Former ID
DNC002714
Drug Name
6-Chloropurine Riboside, 5'-Monophosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
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2D MOL

3D MOL

Formula
C10H12ClN4O7P
Canonical SMILES
C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O
InChI
1S/C10H12ClN4O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKey
ALOBOMYIOYNCBS-KQYNXXCUSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Inosine-5'-monophosphate dehydrogenase 1 Target Info Inhibitor [551393]
Inosine-5'-monophosphate dehydrogenase 2 Target Info Inhibitor [551393]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides de novo biosynthesis
Superpathway of purine nucleotide salvage
Purine nucleotides de novo biosynthesis
Guanosine ribonucleotides de novo biosynthesisPWY-6353:Purine nucleotides degradation
Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway Purine metabolism
Drug metabolism - other enzymes
Metabolic pathwayshsa00230:Purine metabolism
Metabolic pathways
PANTHER Pathway De novo purine biosynthesis
PathWhiz Pathway Purine Metabolism
Reactome Purine ribonucleoside monophosphate biosynthesisR-HSA-73817:Purine ribonucleoside monophosphate biosynthesis
WikiPathways Nucleotide Metabolism
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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