Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0XE0X
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| Former ID |
DCL000698
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| Drug Name |
Aplindore fumarate
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| Synonyms |
Aplindore; Aplindore fumarate (USAN); WAY-DAB-452; (2S)-2-[(benzylamino)methyl]-2,3,7,9-tetrahydro-[1,4]dioxino[2,3-e]indol-8-one; (E)-but-2-enedioic acid; 8H-1,4-Dioxino(2,3-e)indol-8-one,2,3,7,9-tetrahydro-2-(((phenylmethyl)amino)methyl)-,2(S)-, (2E)-2-butenediotate (1:1)
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD9: 295; ICD10:F20] | Phase 2 | [536463] | ||
| Company |
Wyeth
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| Structure |
|
Download2D MOL |
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| Formula |
C22H22N2O7
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| Canonical SMILES |
C1C(OC2=C(O1)C=CC3=C2CC(=O)N3)CNCC4=CC=CC=C4.C(=CC(=O)O<br />)C(=O)O
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| InChI |
1S/C18H18N2O3.C4H4O4/c21-17-8-14-15(20-17)6-7-16-18(14)23-13(11-22-16)10-19-9-12-4-2-1-3-5-12;5-3(6)1-2-4(7)8/h1-7,13,19H,8-11H2,(H,20,21);1-2H,(H,5,6)(H,7,8)/b;2-1+/t13-;/m0./s1
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| InChIKey |
GELJVTSEGKGLDF-QDSMGTAFSA-N
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| CAS Number |
CAS 189681-71-8
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | D(2) dopamine receptor | Target Info | Agonist | [536293], [536463] | |
| References | |||||
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