Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z0PR
|
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| Former ID |
DNC005713
|
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| Drug Name |
L-006235-1
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527882] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C24H30N6O2S
|
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| Canonical SMILES |
CN1CCN(CC1)C2=NC(=CS2)C3=CC=C(C=C3)C(=O)NC4(CCCCC4)C(=O<br />)NCC#N
|
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| InChI |
1S/C24H30N6O2S/c1-29-13-15-30(16-14-29)23-27-20(17-33-23)18-5-7-19(8-6-18)21(31)28-24(9-3-2-4-10-24)22(32)26-12-11-25/h5-8,17H,2-4,9-10,12-16H2,1H3,(H,26,32)(H,28,31)
|
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| InChIKey |
FIVYCSWOCXEWSE-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin S | Target Info | Inhibitor | [527882] | |
| Cathepsin L | Target Info | Inhibitor | [527882] | ||
| Cathepsin B | Target Info | Inhibitor | [527882] | ||
| Cathepsin K | Target Info | Inhibitor | [527882] | ||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Collagen degradation | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Activation of Matrix Metalloproteinases | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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