Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX0TMV
|
||||
| Drug Name |
N-[2-(3-Morpholin-4-yl-ureido)-1-naphthalen-2-ylmethyl-2-oxo-ethyl]-2-[(E)-2-(naphthalene-2-sulfonyl)-vinylamino]-4-phenyl-butyramide
|
||||
| Synonyms |
CHEMBL3142836
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C40H41N5O6S
|
||||
| Canonical SMILES |
O=C(NN1CCOCC1)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCc4ccccc4)N\\C=C\\S(=O)(=O)c5ccc6ccccc6c5
|
||||
| InChI |
InChI=1S/C40H41N5O6S/c46-38(36(19-15-29-8-2-1-3-9-29)41-20-25-52(49,50)35-18-17-32-11-5-7-13-34(32)28-35)42-37(27-30-14-16-31-10-4-6-12-33(31)26-30)39(47)43-40(48)44-45-21-23-51-24-22-45/h1-14,16-18,20,25-26,28,36-37,41H,15,19,21-24,27H2,(H,42,46)(H2,43,44,47,48)/b25-20+/t36-,37-/m0/s1
|
||||
| InChIKey |
PCJKSKCBOVMYIJ-AXSJAOQOSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.