Drug General Information |
Drug ID |
DX1EWG
|
Drug Name |
3-(4-(4-fluorophenyl)piperazin-1-yl)-1-phenylpropan-1-ol
|
Synonyms |
CHEMBL137725
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Formula |
C19H23FN2O
|
Canonical SMILES |
OC(CCN1CCN(CC1)c2ccc(F)cc2)c3ccccc3
|
InChI |
InChI=1S/C19H23FN2O/c20-17-6-8-18(9-7-17)22-14-12-21(13-15-22)11-10-19(23)16-4-2-1-3-5-16/h1-9,19,23H,10-15H2
|
InChIKey |
ZVBKPKJTFRRRND-UHFFFAOYSA-N
|
Target and Pathway |
Target(s) |
5-hydroxytryptamine 1A receptor |
Target Info |
|
[1]
|
Sodium-dependent serotonin transporter |
Target Info |
|
[1]
|
KEGG Pathway
|
cAMP signaling pathway
|
Neuroactive ligand-receptor interaction
|
Serotonergic synapsehsa04726:Serotonergic synapse
|
NetPath Pathway
|
TCR Signaling Pathway
|
PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
|
5HT2 type receptor mediated signaling pathway
|
5HT3 type receptor mediated signaling pathway
|
5HT4 type receptor mediated signaling pathway
|
Reactome
|
Serotonin receptors
|
G alpha (i) signalling events
|
WikiPathways
|
Serotonin HTR1 Group and FOS Pathway
|
SIDS Susceptibility Pathways
|
Monoamine GPCRs
|
GPCRs, Class A Rhodopsin-like
|
GPCR ligand binding
|
GPCR downstream signalingWP727:Monoamine Transport
|
NRF2 pathway
|
Synaptic Vesicle Pathway
|
Serotonin Transporter Activity
|
References |
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |