Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4UM9
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| Drug Name |
(S)-N-(3-(3-(1H-pyrazol-4-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide
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| Synonyms |
CHEMBL561802
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H19N5O2
|
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| Canonical SMILES |
O=C(NCC#N)[C@H](Cc1cccc(c1)c2cn[nH]c2)NC(=O)c3ccccc3
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| InChI |
InChI=1S/C21H19N5O2/c22-9-10-23-21(28)19(26-20(27)16-6-2-1-3-7-16)12-15-5-4-8-17(11-15)18-13-24-25-14-18/h1-8,11,13-14,19H,10,12H2,(H,23,28)(H,24,25)(H,26,27)/t19-/m0/s1
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| InChIKey |
LHNTYJBNWWBALU-IBGZPJMESA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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