Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5PMD
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(1,4-dimethylpiperidin-4-yl)thiazol-4-yl)benzamide
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| Synonyms |
CHEMBL200166
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H33N5O2S
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| Canonical SMILES |
CN1CCC(C)(CC1)c2nc(cs2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C26H33N5O2S/c1-25(12-16-31(2)17-13-25)24-29-21(18-34-24)19-6-8-20(9-7-19)22(32)30-26(10-4-3-5-11-26)23(33)28-15-14-27/h6-9,18H,3-5,10-13,15-17H2,1-2H3,(H,28,33)(H,30,32)
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| InChIKey |
NXSZCSJUPBDVTG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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