Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5QVA
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| Drug Name |
4-Methyl-2-(4''-piperazin-1-yl-biphenyl-3-ylamino)-pentanoic acid cyanomethyl-amide
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| Synonyms |
CHEMBL185431
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H31N5O
|
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| Canonical SMILES |
CC(C)C[C@H](Nc1cccc(c1)c2ccc(cc2)N3CCNCC3)C(=O)NCC#N
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| InChI |
InChI=1S/C24H31N5O/c1-18(2)16-23(24(30)27-11-10-25)28-21-5-3-4-20(17-21)19-6-8-22(9-7-19)29-14-12-26-13-15-29/h3-9,17-18,23,26,28H,11-16H2,1-2H3,(H,27,30)/t23-/m0/s1
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| InChIKey |
MIKDFLKJUSAVHP-QHCPKHFHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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