Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7K3C
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| Drug Name |
3R-(2-oxo-1-(2-oxo-2-(4-oxopent-2-enylamino)ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)methyl 4-chloro-2-(trifluoromethyl)phenylcarbamate
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| Synonyms |
CHEMBL509518
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C31H26ClF3N4O5
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| Canonical SMILES |
CC(=O)\\C=C\\CNC(=O)CN1C(=O)[C@@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)N=C(c3ccccc3)c4ccccc14
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| InChI |
InChI=1S/C31H26ClF3N4O5/c1-19(40)8-7-15-36-27(41)17-39-26-12-6-5-11-22(26)28(20-9-3-2-4-10-20)37-25(29(39)42)18-44-30(43)38-24-14-13-21(32)16-23(24)31(33,34)35/h2-14,16,25H,15,17-18H2,1H3,(H,36,41)(H,38,43)/b8-7+/t25-/m1/s1
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| InChIKey |
TWBMCOZHTPQAMF-LAUDKDLHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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