Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- Cyclin E | (S)-tert-butyl 1-(6-(biphenyl-4-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)propan-2-ylcarbamate | Drug Info |
| CDK2 --- Cyclin E | N-[5-(2-Hydroxy-4,4-dimethyl-pentylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | 6-(3-Hydroxy-propyl)-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 6-(4-Bromo-benzyl)-3-ethyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-9-isopropyl-N6-((3'-methoxybiphenyl-4-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N-(4-tert-Butylamino-2-trifluoromethyl-quinazolin-6-yl)-formamide | Drug Info |
| CDK2 --- Cyclin E | N-[5-(5-tert-Butyl-oxazol-2-ylmethanesulfonyl)-thiazol-2-yl]-isobutyramide | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-3-(pyridin-3-yl)-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-(2-trifluoromethyl-quinazolin-4-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | ((R)-1-Phenyl-ethyl)-(2-trifluoromethyl-quinazolin-4-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | Indenopyrazoles derivative | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-(thiophen-2-yl)pyridin-3-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | (1,1-Dimethyl-propyl)-(2-trifluoromethyl-quinazolin-4-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | N6-(4-(1H-pyrrol-1-yl)benzyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-(4-(pyridin-3-yl)benzyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | Indenopyrazoles derivative | Drug Info |
| CDK2 --- Cyclin E | [5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-carbamic acid benzyl ester | Drug Info |
| CDK2 --- Cyclin E | 6-(3-Amino-2-methyl-benzyl)-3-ethyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 1-[(3-Cyclopropyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-4-((R)-4-hydroxy-3-methylamino-but-1-ynyl)-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | N6-(2,2'-bipyridin-5-ylmethyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N-(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepin-7-yl)methanesulfonamide | Drug Info |
| CDK2 --- Cyclin E | 2-((3,5-diamino-1H-pyrazol-4-yl)diazenyl)phenol | Drug Info |
| CDK2 --- Cyclin E | 1-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-yl]-piperidin-4-ol | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-(pyridin-2-yl)thiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-4-((S)-3-hydroxy-but-1-ynyl)-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | 2-[[6-(Biphenyl-4-ylamino)-9-isopropyl-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | N-(4-Fluorobenzyl)-2-(trifluoromethyl)quinazolin-4-amine | Drug Info |
| CDK2 --- Cyclin E | 7-fluoro-5-(2-fluorophenyl)-3-methyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | 7-chloro-5-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-N6-((3'-chlorobiphenyl-4-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 3-(4-tert-Butylamino-2-trifluoromethyl-quinazolin-6-yl)-benzamide | Drug Info |
| CDK2 --- Cyclin E | (4-Butylsulfanyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-phenyl-methanone | Drug Info |
| CDK2 --- Cyclin E | (3-Isopropyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-urea | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-methoxy-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | N6-(2,3'-bithiophen-5-ylmethyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 2-(5-((2-(2-chloroacetamido)thiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetohydrazide | Drug Info |
| CDK2 --- Cyclin E | 4-(4-Amino-3-hydroxy-but-1-ynyl)-5-fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | Indenopyrazoles derivative | Drug Info |
| CDK2 --- Cyclin E | 6-(thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-amine | Drug Info |
| CDK2 --- Cyclin E | (3-Ethyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-urea | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-N6-((3',4'-dimethylbiphenyl-4-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[6-(4-methoxy-benzylamino)-9-(3-nitro-benzyl)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-(6-furan-2-yl-2-trifluoromethyl-quinazolin-4-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | 2-(5-((2-benzamidothiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetohydrazide | Drug Info |
| CDK2 --- Cyclin E | 4-tert-Butylamino-2-trifluoromethyl-quinazolin-6-ol | Drug Info |
| CDK2 --- Cyclin E | N-[3-(4-Methoxy-phenyl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-2-thiomorpholin-4-yl-acetamide | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-(4-(4-methylthiophen-2-yl)benzyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 4-(1-Hydroxy-2-{[9-isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-yl]-methyl-amino}-ethyl)-benzene-1,2-diol | Drug Info |
| CDK2 --- Cyclin E | N-(3-((2-acetamidothiazol-4-yl)methyl)-5-(cyanomethylthio)-4H-1,2,4-triazol-4-yl)-4-chlorobenzamide | Drug Info |
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