Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(2-chloro-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid 2-(1H-imidazol-1-yl)ethyl ester | Drug Info |
| EGFR3 --- HER2 | (E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-cyano-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-(Bis(2-chloroethyl)amino)-N-(4-isopropylphenyl)benzamide | Drug Info |
| EGFR3 --- HER2 | 5-((4-aminopiperidin-1-yl)methyl)-N-(3-ethynylphenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | 3,4',5-tribromosalicylanilide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-morpholinyl)-2-pentynamide | Drug Info |
| EGFR3 --- HER2 | 1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea | Drug Info |
| EGFR3 --- HER2 | 1-(2-Hydroxy-5-methylbenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-3-(2-(methylamino)ethoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 2-((5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)furan-2-yl)methylamino)acetonitrile | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-((3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl)ethynyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-Pyrrolidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-(3-(4-((isopropylamino)methyl)phenoxy)prop-1-ynyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | [5-(4-amino-piperidin-1-ylmethyl)-pyrrolo[2,1-f][1,2,4]triazin-4-yl]-[3-chloro-4-(1-oxy-pyridin-2-ylmethoxy)-phenyl]-amine | Drug Info |
| EGFR3 --- HER2 | 4-(4-Methoxy-piperidin-1-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-benzyl-1H-indazol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((6-methoxy-1,4-diazepan-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | 2-{2-Chloro-4-[3-cyano-6-(4-dimethylamino-but-2-enoylamino)-7-ethoxy-quinolin-4-ylamino]-phenoxymethyl}-1-methyl-3H-imidazol-1-ium | Drug Info |
| EGFR3 --- HER2 | ethyl 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-7-methyl-6H-pyrrolo[3,4-d]pyridazine-5-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-(5-phenylthiazol-2-ylthio)phenylamino)-3-cyano-7-methoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide | Drug Info |
| EGFR3 --- HER2 | (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-isopropylphenyl)acrylate | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-ethyl-5-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 2-(2-(3,5-Dichloro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-(3-acetamidophenoxy)pyrimidine | Drug Info |
| EGFR3 --- HER2 | N-(4-Chlorophenylsulfonyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetamide | Drug Info |
| EGFR3 --- HER2 | 1-(5-Chloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea | Drug Info |
| EGFR3 --- HER2 | But-2-enedioic acid [4-(3-bromo-phenylamino)-quinazolin-6-yl]-amide (3-dimethylamino-propyl)-amide | Drug Info |
| EGFR3 --- HER2 | N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-(methyl-hydrazonomethyl)-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-amino-6-(1-benzyl-1H-indazol-5-ylamino)pyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-3-(2-(4-methoxypiperidin-1-yl)ethoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-3-(2-(piperazin-1-yl)ethoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(4-benzyloxy-3,5-dichloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-(4-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyanoquinolin-6-yl)-4-morpholinobut-2-enamide | Drug Info |
| EGFR3 --- HER2 | 4-amino-6-(3-chloro-4-fluorophenylamino)pyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | 6,7-dimethoxy-4-(3-nitrophenylamino)quinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | (4-Benzyloxy-3-chloro-phenyl)-{6-[2-(2-methanesulfonyl-ethylamino)-thiazol-4-yl]-quinazolin-4-yl}-amine | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-propynamide | Drug Info |
| EGFR3 --- HER2 | 2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethanol | Drug Info |
| EGFR3 --- HER2 | 4-(4-bromo-3-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Bromophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | AC-480 | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | (3-Chloro-4-fluoro-phenyl)-{6-[2-(2-methanesulfonyl-ethylamino)-thiazol-4-yl]-quinazolin-4-yl}-amine | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(bis(1-methylethyl)amino)-2-butynamide | Drug Info |
| EGFR3 --- HER2 | N4-(3-(6-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)pyrimidin-4-yloxy)phenyl)pyrimidine-4,6-diamine | Drug Info |
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